Characteristic features are risus sardonicus ( a rigid smile ), trismus ( commonly known as " lock-jaw " ), and opisthotonus ( rigid, arched back ).
2.
Gajdusek provided the first medical description of this unique neurological disorder, which was miscast in the popular press as the " laughing sickness " because some patients displayed risus sardonicus as a symptom.
3.
A common symptom of oenanthotoxin is " risus sardonicus ", better known as the Sardonic Grin, coined by Homer in the 8th century BCE, due to the victim's rigid smile after ingestion.
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[Convulsion of the ] facial muscles may cause a characteristic expression called " Risus sardonicus " ( from the Latin for scornful laughter ) or " Risus caninus " ( from the Latin for doglike laughter or grinning ).
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This facial expression has also been observed among patients with tetanus . " Risus sardonicus " causes a patient's eyebrows to rise, eyes to bulge, and mouth to retract dramatically, resulting in what has been described as an evil-looking grin.
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As strychnine poisoning progresses, tachycardia ( rapid heart beat ), hypertension ( high blood pressure ), tachypnea ( rapid breathing ), cyanosis ( blue discoloration ), diaphoresis ( sweating ), water-electrolyte imbalance, leukocytosis ( high number of white blood cells ), trismus ( lockjaw ), risus sardonicus ( spasm of the facial muscles ), and opisthotonus ( dramatic spasm of the back muscles, causing arching of the back and neck ) can occur.
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